• Here we analysed the dynamics of serum

  2018-10-25

  

  Here we analysed the dynamics of serum ovarian hormones, free RANKL, OPG, and the RANKL/OPG complex in BRCA-mutation carriers and wild-type controls throughout the menstrual endothelin receptor antagonists to test whether RANKL and OPG are dysregulated in BRCA-mutation carriers. We further examined

• br Introduction Tumor metabolism is

  2018-10-25

  

  Introduction Tumor metabolism is closely related to tumorigenesis and tumor progression (Burrage et al., 2014; Gill et al., 2016; Nelson et al., 2013; Pike et al., 2011; Sonnet et al., 2016; Watanabe et al., 1984). Gill et al. (2016) presented that the increased rate of glycolysis can support can

• br Discussion Genome wide analyses

  2018-10-25

  

  Discussion Genome-wide analyses of the mammalian transcriptome revealed that lncRNAs is pervasively transcribed in the genome and accumulating studies have demonstrated that lncRNAs as novel regulatory molecule plays critical roles in mammalian development [1,2], but little is known about the pot

• In regions with no grid

  2018-10-25

  

  In regions with no grid connectivity, deployment of small solar power systems can be a key short-term electricity supply strategy. Falling solar home system (SHS) prices (driven by decreases in the cost of photovoltaic panels and batteries) and several market approaches (including piecemeal purchasi

• Fig shows the whole scalp distribution of

  2018-10-25

  

  Fig. 2 shows the whole scalp distribution of VLFO power. At REST both groups showed maximal power along the frontal pole and midline regions. During WORK the VLFO power was lower for both groups although it remained greatest in the frontal pole and centro-parietal areas. Within the ADHD group the C-

• Of particular relevance to the present work

  2018-10-25

  

  Of particular relevance to the present work is evidence that marijuana use during adolescence may have long-lasting effects on emotion (see review in Chadwick et al., 2013). Marijuana use is often co-morbid with mood disorders (Stinson et al., 2006; Swadi and Bobier, 2003), and facets of negative af

• The present findings can be

  2018-10-25

  

  The present findings can be alternatively explained by a progressive enhancement of the neural visual system while children learn to read. In this case, the present changes in alpha adrenergic blockers responses to visual objects would be mainly due to a specific improvement of basic perceptual ski

• There are a large number of

  2018-10-25

  

  There are a large number of reticulated pigmentations that need to be distinguished, including dyskeratosis congenita (DKC), X-linked reticulate pigmentary disorder (XLRPD), Naegeli-Franceschetti-Jadassohn syndrome (NFJS), dermatopathia pigmentosa reticularis (DPR), DDD, reticulate acropigmentation

• The amelanotic melanoma represents of

  2018-10-25

  

  The amelanotic melanoma represents 2–8% of all melanomas. These melanomas have a unique appearance and present a great diagnostic challenge to dermatologists. In addition, the prevalence rate of melanoma is lower in Asians, and the most common subtype is acral lentiginous melanoma. Our patient prese

• A selective maintenance model incorporating economic depende

  2018-10-25

  

  A selective maintenance model incorporating economic dependence was recently presented by Dao et al. [27,28]. Time and cost savings are achieved when several components are simultaneously repaired in a selective maintenance strategy. The authors considered two types of time and cost savings in mult

• cumpli a os en Despu s del n mero Marta

  2018-10-25

  

  cumplió 25 años en 2014. Después del número 50, Marta Lamas, su fundadora y directora hasta ese momento, había decidido concluir el ciclo de la revista. No obstante, conscientes de la enorme importancia del proyecto y del reconocimiento que había logrado tanto en México como en Latinoamérica, las in

• br Myocardial regeneration after allogeneic stem cell therap

  2018-10-24

  

  Myocardial regeneration after allogeneic stem cell therapy Moreover, as outlined above, a consensus is gaining ground that most of the favourable effects of cell transplantation protocols used until now exert their beneficial effect by a paracrine mechanism of the transplanted TAK-875 over the s

• MSCs can express several WNT ligands Cho

  2018-10-24

  

  MSCs can express several WNT ligands (Cho et al., 2006; Etheridge et al., 2004). This endogenous WNT signaling may play a negligible role in MSC expansion, because we found no significant effects on cell proliferation or subsequent differentiation when endogenous WNT proteins were prevented. However

• ibmx However before application in a clinical

  2018-10-24

  

  However before application in a clinical context, a number of issues still need to be considered. Indeed, SSC transplantation in cancer patients requires techniques to exclude cancer cell contamination, because implantation of as few as 20 leukemic ibmx can result in cancer relapse (Jahnukainen et

• Cancer cells use epigenetic mechanisms to control

  2018-10-24

  

  Cancer 5-aminolevulinic acid use epigenetic mechanisms to control tumor growth, invasion, and resistance to therapy. Novel therapeutic approaches targeting epigenetic modifications are considered the new frontier in cancer therapy. In fact, pharmacological modulation of epigenetic alterations is ex

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