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Discussion Previous study has shown that one
2019-04-30

Discussion Previous study has shown that one of the most important characteristics of music is that of reducing anxiety. The mechanism of music therapy is thought to arise from multiple nervous stimuli that are conducted into the brain, which are antagonists to each other, and under certain conditi
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Early repolarization is often also observed in Brugada syndr
2019-04-30

Early repolarization is often also observed in Brugada syndrome patients [30–34]. In this study, 34% of Brugada syndrome patients exhibited early repolarization in inferolateral leads. Clinical characteristics, inducibility, and arrhythmic event rate were similar between patients with and without ea
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ldh assay Recently emerging data suggest that lower frequenc
2019-04-30

Recently emerging data suggest that lower frequency of IV bisphosphonates in metastatic breast cancer has the same efficacy as monthly regimen [48]. ONJ on the other hand can be extremely symptomatic with a severely detrimental effect on quality of life. A case-control study based on risk factors f
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Dyslipidemia is characterized by increased
2019-04-30

Dyslipidemia is characterized by increased total cholesterol, LDL-C, and triglyceride levels, and decreased HDL-C levels. However, the association of ApoA1 polymorphism with serum HDL-C level remains controversial. The polymorphisms of ApoA1+84 TC, but not MspI, are associated with serum HDL-C. The
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Numerous clinical trials phase II and phase III have
2019-04-30

Numerous clinical trials (phase II and phase III) have been then designed to evaluate the efficacy of denosumab in oncology mainly in breast and prostate bone metastases (Table 1). These studies revealed that denosumab reduced significantly bone turnover markers similarly to osteoporotic patients. M
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The conventional cutoff for small for gestational age is bas
2019-04-30

The conventional cutoff for small for gestational age is based on birthweight, which is suitable for infants born at term but is far less appropriate for those born preterm. Preterm birth is itself pathological, and ultrasound-based estimates of fetal weight show that infants born preterm are much s
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Since the Food Safety Standards
2019-04-30

Since 2006, the Food Safety Standards Authority of India has led efforts to promote food safety, tighten food laws, and harmonise these laws with international standards and quality-management systems. These efforts need to be complemented with interventions focused on practices at the household lev
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br Tara Mangal and colleagues document the struggle
2019-04-30

Tara Mangal and colleagues document the struggle to eliminate polio in northern Nigeria. However, they overlook the importance of routine immunisation to polio eradication efforts. The investigators identified an association between the risk of contracting polio and oral polio vaccine unavailabil
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Cuando Gonzalo Pizarro se alz en el Per nunca mostr
2019-04-30

Cuando Gonzalo Pizarro se alzó en el Perú, nunca mostró intenciones de romper los vínculos que lo unían RPC1063 su rey, por mucho que su plan fuese establecer una monarquía, autónoma de la castellana, que gobernaría el territorio. En las misivas que envió al monarca, Pizarro confirmaba su obediencia
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In conclusion describing a single
2019-04-30

In conclusion, describing a single case observation of a PV-patient we have for the first time delivered the “proof of concept” that combination therapy with Rux and “low-dose” IFN is safe, tolerable and highly efficacious in PV, as evidenced by a rapid reduction in the JAK2V617F-allele burden in co
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Perhaps the greatest challenge however relates to the epidem
2019-04-30

Perhaps the greatest challenge however, relates to the epidemiology of this disease and understanding the interactions that occur between the reservoir hosts (ie, monkeys), vectors, and human activities that enable transmission. Understanding these complex behavioral and ecological interactions will
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Although SCN A variants account for of BrS SCN
2019-04-29

Although SCN5A variants account for 18–28% of BrS [196], SCN5A genetic testing is complicated by an approximately 3–5% “benign” variant frequency in the general population [194]. Therefore, even in the most common genetic cause of BrS, 1 in 10 “positive” tests could be a “false- positive” even if fo
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Los cl rigos que lograban hacerse de algunos
2019-04-29

Los clérigos que lograban hacerse de algunos medios movían su dinero continuamente buy olda través de préstamos, inversiones en bienes raíces o en ganado, y también se convertían en socios de compañías mercantiles y de otras empresas. La situación se facilitaba por los vínculos y redes que forjaban
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br En hab a un buen
2019-04-29

En 1950 había un buen número de publicaciones culturales circulando por Latinoamérica. Entre ellas sobresalían dos, que fueron paradigmáticas para la tradición literaria por su particular apuesta universalista: Sur —que se publicó regularmente en Buenos Aires entre 1931 y 1970— y Orígenes —que vio
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Presence of trisomy raises the possibility of added gene dos
2019-04-29

Presence of trisomy raises the possibility of added gene dose contributing to the leukemogenic process. The oncogene, c-kit, is localized to chromosome 4. Leukemic blasts of our patient strongly expressed c-kit. c-Kit expression was not studied in the other 4 reported cases of MPAL. Increased expres
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