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We describe a novel case
2019-06-24
We describe a novel case, wherein a patient with AML with inv (16) underwent allogeneic bone marrow transplantation from a related sibling donor which contained a small subpopulation of premalignant stem nonreceptor tyrosine kinase with trisomy 11. Fourteen years following transplantation, this pat
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br Conclusion br Introduction Multiple myeloma is a malignan
2019-06-24
Conclusion Introduction Multiple myeloma is a malignant plasma cell disorder, comprising approximately 10% of all haematological malignancies, and its incidence is increasing [1]. The pathogenesis is complex, culminating in malignant transformation of clonal plasma cells. The aetiology is not
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Because of the high amplitude
2019-06-24
Because of the high amplitude of atrial signals, atrial sensitivity was decreased from 0.5mV to 0.7mV to 1.0mV. As the sensitivity decreased, atrial sensing was restored gradually. With the sensitivity of 1.0mV, normal atrial sensing with mode switching was restored completely. The sensitivity was p
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TEE guidance can also be helpful during pulmonary vein cryoa
2019-06-21
TEE guidance can also be helpful during pulmonary vein cryoablation for AF. Kerut et al. [9] described their first 20 cases of cryoablation for AF using TEE and found TEE to have better overall procedural imaging and monitoring for pericardial effusion or thrombus formation. They found TEE monitorin
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Methyllycaconitine citrate br Autophagy and lipid metabolism
2019-06-21
Autophagy and lipid metabolism LD formation is an indispensable step in lipid metabolism. The Atg8/LC3 conjugation system is essential for autophagosome membrane formation. However, some evidence suggests that Atg8/LC3 conjugation is also involved in LD formation. Indeed, LD formation is suppress
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Much of the focus of expert and
2019-06-21
Much of the focus of expert and public attention has been on HIV treatment, including test and treat (ie, treatment as prevention) strategies. This is understandable. Treatment for HIV has become extraordinarily effective, costs have dropped substantially during the past two decades, and the potenti
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En textos m s recientes Aboy Carl s profundiza
2019-06-21
En textos más recientes, Aboy Carlés profundiza esta distinción y reconoce que no toda identidad tiene una pretensión hegemónica y propone distinguir entre identidades totales, identidades parciales e identidades con pretensión hegemónica de acuerdo con el modo de procesar la relación entre la parte
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Upon diagnosis the patient s lymphoma and HLH represented
2019-06-21
Upon diagnosis, the patient׳s lymphoma and HLH represented a therapeutic dilemma. Effective early therapy reduces mortality of HLH from 95% to 30–35% [4]. The HLH-2004 treatment protocol consists of T-cell targeted immunosupression with dexamethasone and cyclosporine, macrophage targeted etoposide w
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br Methods br Results Globally CCI increased by percent
2019-06-21
Methods Results Globally, CCI increased by 0·82 percent points a year, from 54·8% in 1994, to 71·2% in 2014 (CCI estimates at national level, stratified by wealth quintiles and place of residence, are presented in the appendix, pp 6–15). This gain was largely driven by low-income countries, wh
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Fig shows the percentage of patients with
2019-06-21
Fig. 2 shows the percentage of patients with high D-dimer levels in relation to the CHA2DS2–VASc scores and BNP levels. None of the patients had a CHA2DS2–VASc score of 0. The BNP levels were elevated in 3 (38%) of the 8 patients with CHA2DS2–VASc scores of 1, and the D-dimer levels were elevated in
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The re treatment of metastatic
2019-06-21
The re-treatment of metastatic bone disease causing recurrent pain after an initial course of EBRT was seen to be feasible with a reasonable rate of symptom relief [13–19]. In echoing the ACR findings, the task force noted that the available data was derived from studies where re-treatment was not t
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br Material and methods br Results br
2019-06-21
Material and methods Results Discussion PV isolation is currently the cornerstone for treatment of patients with paroxysmal AF [6]. An extended technique is circumferential PV isolation using point-by-point ablation around the PV ostium. However, that is a technically challenging and time-c
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br Results Compared to the respective
2019-06-21
Results Compared to the respective untreated groups, the VT duration was shorter in clonidine-treated ETB-deficient rats during phase I and in wild-type rats during phase II (Fig. 1A). Heart rate (HR) increased in both untreated groups, but this response was blunted after clonidine, mainly in ETB
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OS is Executive Director of the
2019-06-21
OS is Executive Director of the INDEPTH Network. PB is Director of the WHO Collaborating Centre for Verbal Autopsy and chairs the Scientific Advisory Committee of the INDEPTH Network. The INDEPTH Network is grateful for core funding from Sida, the Wellcome Trust, and the William & Flora Hewlett Foun
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However Ethiopia is addressing this situation head on To
2019-06-20
However, Ethiopia is addressing this situation head-on. To increase access to oxygen and pulse oximetry, the Ethiopian Ministry of Health (MOH) has responded by undertaking a comprehensive strategic planning process captured as a roadmap for oxygen and pulse oximetry scale-up. A national technical w
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