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The CLC proteins in Arabidopsis have
2020-07-28

The CLC proteins in Arabidopsis have been studied in some detail, and a total of seven genes (named AtCLCa-AtCLCg) have been identified (Lv et al., 2009). It is interesting that AtCLCa-AtCLCd and AtCLCg define a distinct phylogenetic branch that is closely related to eukaryotic CLCs, while the other
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RecBCD is a combination helicase nuclease that
2020-07-27

RecBCD is a combination helicase/nuclease that is critical to homologous genetic recombination and DNA repair in E. coli., The holoenzyme consists of the three subunits RecB, RecC, and RecD. The RecB and RecD subunits are NTP hydrolysis-dependent DNA motor proteins that drive DNA translocation and s
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In the present study we described the
2020-07-27

In the present study, we described the cloning and sequencing of a G3DH gene from Rhizobium sp. S10 and its co-expression in E. coli. The recombinant enzyme, identified as rG3DH, was consequently purified, characterized and utilized in d-gulose production. Materials and methods Results Disc
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Studies have shown that the cultivation of
2020-07-27

Studies have shown that the cultivation of BMSCs under hypoxic conditions, treating with cytokines (such as HGF, IGF-1 and IL-6) and viral-mediated CXCR-4 gene delivery have been shown to re-establish CXCR-4 expression on the surface of stem Auranofin (Liu et al., 2010, Liu et al., 2014a, Ziaei et a
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CHIR-98014 We have previously characterized the leucine rich
2020-07-27

We have previously characterized the leucine-rich NESs located within the zinc-binding domains of mucosal high risk HPV16 E7 (76IRTLEDLLM84) and low risk HPV11 E7 (76IRQLQDLLL84) mediating their nuclear export in a CRM1 dependent manner (Knapp et al., 2009, McKee et al., 2013). The zinc-binding doma
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Prior studies of accelerated learning hypothesize
2020-07-27

Prior studies of accelerated learning hypothesize that non-traditional students are more mature and motivated than traditional students (Van Scoyc and Gleason, 1993, Charron and Lowe, 2009). We employ age in years at the time of program completion (AGE) as a proxy for the motivational impacts of pre
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br Preparation of Recombinant Proteins br Activity Assays
2020-07-25

Preparation of Recombinant Proteins Activity Assays The following solvents are used in the procedures described in this section: Data Analysis Aryl radical rearrangements typically result in a large number of products being generated by Bmp7. Approaches combining mass spectrometry and NMR
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Unexpectedly CRF receptor agonist and antagonist evoked
2020-07-25

Unexpectedly, CRF2 receptor agonist and antagonist evoked similar effects in the fall in tail skin temperature caused by restraint. However, Ucn3 reduced basal values of tail skin temperature, thus indicating that some degree of basal vasoconstriction caused by BNST treatment with Ucn3 may have cont
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The CPA EoS was presented
2020-07-25

The CPA EoS was presented by Kontogeorgis et al., in 1996 [23]. The proposed equation is composed of two parts (SRK EOS + association term) such that it can well predict the thermodynamic behavior of hydrogen bonding materials as a result of considering the association term. Yakoumis et al. (1997) e
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Survival analysis has been widely used in medical
2020-07-25

Survival analysis has been widely used in medical science, economics, finance, and social science, among others. In many studies, survival data have primary outcomes or responses that are subject to censoring. The Cox model [7], [8] is the most commonly used regression model for survival data, and t
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Does hydroxylation of proline have
2020-07-25

Does hydroxylation of proline have a specific role in the structure and function of the conotoxins? Several studies in the literature provide insights into the role of proline hydroxylation in the Conus peptides. The consequences of proline hydroxylation on oxidative folding and biological activity
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br Conflict of interest statement br Acknowledgement
2020-07-25

Conflict of interest statement Acknowledgement The research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement n° 278742 (Eurosarc) Introduction Pseudomyogenic hemangioendothelioma/epithelioid sarcoma-like
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Preliminary studies suggest that dimerization of the AT rece
2020-07-25

Preliminary studies suggest that dimerization of the AT1 receptor occurred during the biosynthesis in the endoplasmic reticulum before surface expression [27,40], which may explain the presenece of these lp-pla2 inhibitor before the addition of any ligand. Our results showed that the presence of A
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We also identified Ubc as a
2020-07-25

We also identified Ubc13 as a functional E2 for LNX1 and determined the complex structure of LNX1–Ubc13~Ub, which depicts the first step of the ubiquitination process (Fig. 3a.). Comparing structural alignment of the RNF4 RING: Ubc13~Ub: Ube2V2 complex (PDB code 5AIU) [33] and the RNF4:Ubc13~Ub comp
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For the SAR optimization of the right
2020-07-25

For the SAR optimization of the right hand side, it was decided to explore the inclusion of the key carboxylic Cy5 TSA moiety present in the original DGAT-1 inhibitors from . Analogs were constructed by the synthetic routes outlined in , . In , the methylene-oxy linker was introduced by condensatio
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