• Protease Inhibitor Cocktail (100X in DMSO, EDTA plus) recept

  2022-03-22

  

  To our knowledge, the putative role of ET-1 and ETB-R in oligodendroglioma progression was not documented so far. Using primary cultures of grade B oligodendroglial tumor cells, we have here assessed the functionality of ETB-R expression in these tumors. Confocal microscopy analysis confirmed the st

• Histamine modulates an attentional state which might affect

  2022-03-22

  

  Histamine modulates an attentional state, which might affect performances in the object recognition test. Indeed, systemic injection of H3 receptor inverse agonists enhances the attentional state (41). However, the memory recovery in our study is unlikely to be due to the enhanced attentional state.

• Allergic rhinitis characterized by inflammation of the nasal

  2022-03-22

  

  Allergic rhinitis, characterized by inflammation of the nasal membrane, results from an over-activated immune system exposed to Deoxycholic acid in sensitized individuals, and is associated with nasal congestion, rhinorrhea, sneezing, and pruritus. As histamine is a key mediator in triggering aller

• br Recently MST emerged as a critical regulator of

  2022-03-22

  

  Recently, MST1 emerged as a critical regulator of leukocyte function and autoimmunity in humans. Five independent groups reported on autosomal recessive nonsense mutations in the gene STK4 (which encodes for MST1) in human patients with a novel primary immunodeficiency disease (PID), now called ST

• ICLs represent of all generated DNA adducts for

  2022-03-21

  

  ICLs represent ICL Inducers in Cancer Therapy Nitrogen mustards with aromatic substituents (chlorambucil, melphalan) or a bioactivatable phosphoramide group (cyclophosphamide) were one of the first identified DNA crosslinkers. These agents are still used in combined schemes for the therapy of chr

• Since its development the HCV replicon system Lohmann et

  2022-03-21

  

  Since its development, the HCV replicon system (Lohmann et al., 1999) has been a critical tool in the HCV antiviral discovery process (Gottwein et al., 2009, Imhof and Simmonds, 2010, Lohmann et al., 1999, Pietschmann et al., 2001, Imhof and Simmonds, 2010, Gottwein et al., 2009). The replicon assay

• We found few differential effects on lung function for expos

  2022-03-21

  

  We found few differential effects on lung function for exposure to mother’s and father’s smoking in relation to GSTM1 and GSTT1. However, effects related to mother’s or father’s smoking may differ because mothers tend to spend greater amounts of time with young children and mothers may also smoke du

• Despite the rapid development of synthetic ligands the endog

  2022-03-21

  

  Despite the rapid development of synthetic ligands, the endogenous ligands of GPR109A, GPR109B and GPR81 remained elusive until recently. This is probably the result of their relatively low potencies and their metabolite character (Table 1). Traditionally, agonists of GPCRs were believed to belong t

• br Material and methods br Results The

  2022-03-21

  

  Material and methods Results The search for proteins selectively expressed in pancreatic islet Methicillin sodium salt synthesis in the Human Protein Atlas (HPA) yielded 27 hits, including well-known islet cell markers such as insulin, glucagon and pancreatic polypeptide (Table 1). The search

• Initial evidence that cell contact mediated transmission

  2022-03-21

  

  Initial evidence that cell-contact-mediated transmission of HIV-1 is relevant for the generation of latently infected notch signaling was suggested in the context of transmission from dendritic cells to resting CD4+ T cells (Evans et al., 2013, Kumar et al., 2015). As dendritic cells probe for anti

• Diabetes induced damage results in peripheral nerve patholog

  2022-03-21

  

  Diabetes-induced damage results in peripheral nerve pathology that Rifabutin correlates with clinical signs and symptoms. Nerve injury that results in structural changes can be measured through clinical neurological assessment, quantitative sensory testing, nerve conduction studies, and peripheral

• br Methods and materials br Results To examine the fear

  2022-03-21

  

  Methods and materials Results To examine the fear conditioning effects of the pre-exposure, drug, and sex factors in the total latency time, a 2 × 3 × 2 three-way ANOVA indicated that phosphodiesterase inhibitors significant differences occurred in the drug (F2109 = 14.44, p 0.05) and pre-exp

• Glucose uptake a critical metabolic control point in

  2022-03-21

  

  Glucose uptake, a critical metabolic control point in glycolysis, is mediated by the GLUT (SLC2) family of integral membrane transporters (Mueckler and Thorens, 2013). GLUT1 (SLC2A1), one of the most well-studied members of the SLC2 family, exhibits a wide tissue distribution; cell surface expressio

• glycine receptors Nano SiO was a kind of versatile

  2022-03-21

  

  Nano-SiO2 was a kind of versatile material for enzyme immobilization because of its excellent properties, including low cost, lack of toxicity, high stability, large specific surface area and high biocompatibility [10]. After the immobilization on nano-SiO2, the selectivity of enzymatic reactions wo

• T7 High Yield RNA Recently several dual GLP GIP

  2022-03-21

  

  Recently, several dual GLP-1/GIP receptor agonists have been developed as a treatment of type II diabetes. These peptides can activate both the GLP-1 and the GIP receptor. Such dual receptor agonists are superior compared to single GLP-1 analogues such as liraglutide (Finan et al., 2013). Previously

16430 records 499/1096 page Previous Next First page 上5页 496497498499500 下5页 Last page