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Interestingly the inverse is also
2018-11-12

Interestingly, the inverse is also true. In its intense appearance without a sufficient view, artificial bright light can give a positive effect on human well-being, particularly for healing purpose (e.g., Eastman et al., 1998; Lingjærde et al., 1998; Avery et al., 2001). Many specific lighting prod
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br Results The patients were followed up for
2018-11-12

Results The patients were followed up for 3–22 months (mean: 8 months). There was no visual impairment, new-onset extraocular movement limitation, or wound infection after surgery. The CT scan revealed that all patients had their mesh placed adequately without incarceration of orbital contents or
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Obesity in general is a predisposing
2018-11-12

Obesity in general is a predisposing factor of OA. There is a strong association between overweight and hip and knee OA. However, the association between overweight and ankle OA remains unclear. In Frey and Zamora\'s study regarding overweight and ankle OA, a total of 887 women and 535 men were incl
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br Case report A year old boy
2018-11-12

Case report A 3-year-old boy with a history of traumatic subarachnoid hemorrhage and skull fracture at age 1.5 months developed hydrocephalus and underwent VPS at 9 months. At 18-months old, the VP shunt was replaced with a new shunt because of infection. Eighteen months later, he experienced abd
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br Clinical trials of ketogenic
2018-11-12

Clinical trials of ketogenic diets in AD Oral administration of medium chain triglycerides has been shown to induce ketosis in humans [66]. Due to their short fatty adipor1 chain lengths, medium chain trigycerides do not underlie the regulation imposed on long chain fatty acids and they undergo
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LDS BBs were found to
2018-11-12

LDS BBs were found to respond to ET-1 stimulation with a decrease in cell shortening. Furthermore, our findings that BQ123, but not BQ3020, blocked the negative shortening response to ET-1 are consistent with those of Izumi and co-workers (Izumi et al., 2000) and indicate an ETA receptor-mediated ef
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br Results br Discussion Supplementation
2018-11-12

Results Discussion Supplementation of the p38 MAPK inhibitor SB203580 has been identified to enhance cardiomyogenesis of human embryonic stem PXD101 at a relative narrow range of 1–10μM whereas higher concentrations >15μM inhibited or blocked cardiac differentiation (Graichen et al., 2008). T
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Previous reports have suggested that WNTs modulate BMP signa
2018-11-12

Previous reports have suggested that WNTs modulate BMP signaling by promoting C-terminal phosphorylation of SMAD1/5, key components of the BMP signal transduction pathway (Fuentealba et al., 2007). Therefore, we compared the phosphorylation of SMAD1/5 in EBs formed in the combination of WNT3A/BMP4 t
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To the best of our knowledge only
2018-11-12

To the best of our knowledge, only three metabolites, L-threonine, butyrate, and vitamin C, have been identified so far that act as epigenetic modulators of ESC self-renewal and/or somatic cell reprogramming (Mali et al., 2010; Shyh-Chang et al., 2013; Wang et al., 2009). Interestingly, L-threonine,
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In conclusion the present study utilized an in vivo
2018-11-12

In conclusion, the present study utilized an in vivo piglet model of hypoxic-preconditioning-induced ischemic tolerance to demonstrate that PC induces proliferation and neurogenesis of endogenous NSPs up to 7days after the hypoxic–ischemic insult. PC appears as a broad, non-invasive and reproducible
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ldv cost Several transcripts that exhibited an expression ch
2018-11-12

Several transcripts that exhibited an expression change triggered by T3 are promising candidates for being responsible for the observed increased cell extension growth of ENS cells in vitro. The calcium dependent cell adhesion molecule cadherin 12 (Cdh12, N-cadherin, 5.6 fold upregulated), the gene
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br Introduction Human embryonic and induced
2018-11-12

Introduction Human embryonic and induced pluripotent stem cells (h/iPSCs) are of considerable interest in developmental biology and regenerative medicine, representing an enormous opportunity for generating patient-specific cells for screening drugs and cell therapies for various diseases. Stem c
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br Acknowledgements This work was supported by the IRET Foun
2018-11-09

Acknowledgements This work was supported by the IRET Foundation (2015-2016), Ozzano Emilia, Italy (no-profit organization), in the frame of the “Step-by-step” POR-FESR 2016-2020 Emilia Romagna Region project. Introduction Resident neural stem cells (NSCs) persist in the adult mammalian centra
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b-raf inhibitors A growing amount of evidence indicates
2018-11-09

A growing amount of evidence indicates that PSCs initiate their differentiation program from the G1 phase of the b-raf inhibitors where they are most susceptible to specification cues (Chetty et al., 2013; Jonk et al., 1992; Mummery et al., 1987; Pauklin and Vallier, 2013; Sela et al., 2012; Singh e
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Several studies have linked expression of CD
2018-11-09

Several studies have linked expression of CD44 and MMP14 to the CSC population. Data suggest common mechanisms regulating co-expression of these two genes; blockade of the ERK pathway suppressed expression of CD44 and MMP14 and inhibited invasiveness of cancer leukotriene receptor antagonist (Tanimu
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