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A marked increase in erythrocyte PMRS activity was observed
2018-10-29
A marked increase in erythrocyte PMRS activity was observed in HgCl2 challenged rats as compared to control (P Discussion Oxidative stress is a deleterious condition that occurs when there is damage to cellular components, including proteins, lipids, and DNA [6]. Mercuric chloride (HgCl2) is one o
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br Materials and methods br Results br
2018-10-29
Materials and methods Results Discussion Free radical damage can be considered as one of the major causative factors involved in many diseases such as inflammation and dementia. It is well established that anti-oxidants are capable of preventing injury to blood vessel membranes, thereby opt
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Environmental samples may contain mixed populations
2018-10-29
Environmental samples may contain mixed populations of STEC strains, many of which could share O-type GSK503 with a variety of H-antigens. It has been suggested that identifying fliC gene type may be helpful for detection of pathogenic STEC strains. Several H-types including H-, H2, H7, H8, H11, H1
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br Results br Discussion Cell therapy using hESCs has receiv
2018-10-29
Results Discussion Cell therapy using hESCs has received a great deal of attention following the initial hESC culture techniques reported in 1998 (Thomson et al., 1998). However, the application of hESCs in clinical cell therapy is limited because current culture conditions have certain disadv
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br Materials and methods br Statistical analyses Results wer
2018-10-29
Materials and methods Statistical analyses Results were expressed as mean±SEM (standard error of mean). Multiple group comparisons were performed by one-way analyses of variance (ANOVA) followed by the Bonferroni procedure for comparison of means. Comparisons between two groups were performed
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has reached the significant milestone of five years in publi
2018-10-29
has reached the significant milestone of five years in publication and, as Editor-in-Chief, I would like to thank our publisher, Elsevier, the journal editors and our reviewers for their hard work, dedication and support in launching and establishing a new journal in the stem cell field. Most of all
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br Results br Discussion We first identified surface markers
2018-10-29
Results Discussion We first identified surface markers that distinguish the earliest prechondrocytes from nonchondrogenic factor xa inhibitors types; subsequent comparison of prechondrocytes with differentiated, definitive resting (immature) chondrocytes located in the superficial periarticul
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In the present study we introduce
2018-10-26
In the present study, we introduce a novel cell surface protein, CD98, that is specifically expressed on the cells of the basal layer and, in addition, remains stably expressed after a multitude of proteolytic treatments. We show that purified CD98high cells are able to induce tumor growth upon seri
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CM-272 Our study reports that the
2018-10-26
Our study reports that the loss of Klf5 from intestinal stem CM-272 leads to reduction in proliferation eventually resulting in the loss of stem cells. We propose three possible outcomes of Klf5 deletion in stem cells that could elucidate our findings. Firstly, the replenishment of the TA cell popu
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In our study for CD depleted cells seeded on
2018-10-26
In our study, for CD3depleted cells seeded on BMSC feeder cells in the presence of all cytokines, there was a significant decrease in the expression of CD3, CD19, CD14 and CD15 on day 14 compared to day 0. Our finding of no significant expression of these markers on CD3depleted cells suggests that t
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For live cell imaging we established a well
2018-10-26
For live-cell imaging, we established a 96-well plate-based screening assay to assess expression of the pluripotency-associated surface marker TRA-1-60, a more reliable and specific marker for predicting successful reprogramming and iPS cell derivation than other markers including AP (Mali et al., 2
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br Results br Discussion CSL serves as the central
2018-10-26
Results Discussion CSL serves as the central node in canonical Notch signaling by transmitting signaling from all Notch receptors upon ligand activation. In this work, we report that genetic ablation of CSL in breast tumor methylergometrine cost leads to enhanced tumor growth after transplanta
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Aside from the benefits of the actual protocol our
2018-10-26
Aside from the benefits of the actual protocol, our method also results in hiNSCs with multiple favorable properties including a seemingly endless capacity for self-renewal. hiNSC colonies grown on MEF feeders are approximately 50% positive for proliferation marker Ki67, a characteristic that does n
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Whether alternate in vitro pluripotent states have any
2018-10-26
Whether alternate in vitro pluripotent states have any functional significance is an important question. Indeed, despite inducing broad transcriptional/epigenetic differences, the assayed culture conditions are still all capable of supporting naive pluripotency, implying that activation of the core
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br The technique of processing the
2018-10-26
The technique of processing the time series of solar flare HXR The technique of processing the experimental data obtained using the BATSE spectrometer for simple single-pulse events is described in Ref. [3]. In essence, the technique entails constructing a mutual correlation function (MCF) for al
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