• has reached the significant milestone of five years in publi

  2018-10-29

  

  has reached the significant milestone of five years in publication and, as Editor-in-Chief, I would like to thank our publisher, Elsevier, the journal editors and our reviewers for their hard work, dedication and support in launching and establishing a new journal in the stem cell field. Most of all

• br Results br Discussion We first identified surface markers

  2018-10-29

  

  Results Discussion We first identified surface markers that distinguish the earliest prechondrocytes from nonchondrogenic factor xa inhibitors types; subsequent comparison of prechondrocytes with differentiated, definitive resting (immature) chondrocytes located in the superficial periarticul

• In the present study we introduce

  2018-10-26

  

  In the present study, we introduce a novel cell surface protein, CD98, that is specifically expressed on the cells of the basal layer and, in addition, remains stably expressed after a multitude of proteolytic treatments. We show that purified CD98high cells are able to induce tumor growth upon seri

• CM-272 Our study reports that the

  2018-10-26

  

  Our study reports that the loss of Klf5 from intestinal stem CM-272 leads to reduction in proliferation eventually resulting in the loss of stem cells. We propose three possible outcomes of Klf5 deletion in stem cells that could elucidate our findings. Firstly, the replenishment of the TA cell popu

• In our study for CD depleted cells seeded on

  2018-10-26

  

  In our study, for CD3depleted cells seeded on BMSC feeder cells in the presence of all cytokines, there was a significant decrease in the expression of CD3, CD19, CD14 and CD15 on day 14 compared to day 0. Our finding of no significant expression of these markers on CD3depleted cells suggests that t

• For live cell imaging we established a well

  2018-10-26

  

  For live-cell imaging, we established a 96-well plate-based screening assay to assess expression of the pluripotency-associated surface marker TRA-1-60, a more reliable and specific marker for predicting successful reprogramming and iPS cell derivation than other markers including AP (Mali et al., 2

• br Results br Discussion CSL serves as the central

  2018-10-26

  

  Results Discussion CSL serves as the central node in canonical Notch signaling by transmitting signaling from all Notch receptors upon ligand activation. In this work, we report that genetic ablation of CSL in breast tumor methylergometrine cost leads to enhanced tumor growth after transplanta

• Aside from the benefits of the actual protocol our

  2018-10-26

  

  Aside from the benefits of the actual protocol, our method also results in hiNSCs with multiple favorable properties including a seemingly endless capacity for self-renewal. hiNSC colonies grown on MEF feeders are approximately 50% positive for proliferation marker Ki67, a characteristic that does n

• Whether alternate in vitro pluripotent states have any

  2018-10-26

  

  Whether alternate in vitro pluripotent states have any functional significance is an important question. Indeed, despite inducing broad transcriptional/epigenetic differences, the assayed culture conditions are still all capable of supporting naive pluripotency, implying that activation of the core

• br The technique of processing the

  2018-10-26

  

  The technique of processing the time series of solar flare HXR The technique of processing the experimental data obtained using the BATSE spectrometer for simple single-pulse events is described in Ref. [3]. In essence, the technique entails constructing a mutual correlation function (MCF) for al

• One potential criticism of this multidimensional scale that

  2018-10-26

  

  One potential criticism of this multidimensional scale that measures perceptions of child spiritual health is that it insulin receptor is operationally very similar to other psychological constructs. The latter include measures of well-being, life satisfaction, and emotional health. These constructs

• With similarities and differences in social economic and pol

  2018-10-26

  

  With similarities and differences in social, economic, and political contexts in Canada and the United States, it dpn has been suggested that comparing these two countries holds important insights for understanding how structural determinants, such as social policies and economic resources, shape i

• A pragmatic trial program highlights the tension

  2018-10-26

  

  A pragmatic trial program highlights the tension between two perspectives of clinical research. In the traditional view, all clinical research puts patients at risk and therefore they must be protected through informed consent. In the pragmatic triallist’s view, the fact that both treatment arms rep

• Satisfaction with CSR initiatives therefore

  2018-10-26

  

  Satisfaction with CSR initiatives therefore becomes a key metric of the successful development and implementation of a CSR policy. Consumers may wish to reward companies with good CSR records positively or even with non-negative information in the form of resilience to negative information about the

• Small scale systems or POU systems have become the most

  2018-10-26

  

  Small scale systems or POU systems have become the most suitable methods of treatment in the rural areas as it has many advantages. It does not require large volumes of water and is not affected by difficult topography or dispersed settlement. Most small scale systems may not require electricity (So

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