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With increasing usage of colistin as
2018-11-12
With increasing usage of colistin as the last therapy for many refractory clinical infections, resistance to colistin is becoming more widespread. Taken together, the data clearly show that the principal mechanism of colistin resistance in the Col-R and Col-D clinical A. baumannii strains is the los
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br Introduction Empirical studies on
2018-11-12
Introduction Empirical studies on the cognitive activity of design in architectural design education are increasing slowly but steadily. Many researchers have investigated action analysis, working memory, imagery reinterpretation, and mental synthesis of designers (e.g., Suwa et al., 1998; Gero a
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These results showed that the
2018-11-12
These results showed that the intensities of solar radiation incidence on the roof varied depending on the colour and thermo-physical properties of the roof. Givoni (1994) showed that the the difference in the maximum external surface temperature between a black and white roof in the desert during s
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Interestingly the inverse is also
2018-11-12
Interestingly, the inverse is also true. In its intense appearance without a sufficient view, artificial bright light can give a positive effect on human well-being, particularly for healing purpose (e.g., Eastman et al., 1998; Lingjærde et al., 1998; Avery et al., 2001). Many specific lighting prod
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br Results The patients were followed up for
2018-11-12
Results The patients were followed up for 3–22 months (mean: 8 months). There was no visual impairment, new-onset extraocular movement limitation, or wound infection after surgery. The CT scan revealed that all patients had their mesh placed adequately without incarceration of orbital contents or
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Obesity in general is a predisposing
2018-11-12
Obesity in general is a predisposing factor of OA. There is a strong association between overweight and hip and knee OA. However, the association between overweight and ankle OA remains unclear. In Frey and Zamora\'s study regarding overweight and ankle OA, a total of 887 women and 535 men were incl
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br Case report A year old boy
2018-11-12
Case report A 3-year-old boy with a history of traumatic subarachnoid hemorrhage and skull fracture at age 1.5 months developed hydrocephalus and underwent VPS at 9 months. At 18-months old, the VP shunt was replaced with a new shunt because of infection. Eighteen months later, he experienced abd
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br Clinical trials of ketogenic
2018-11-12
Clinical trials of ketogenic diets in AD Oral administration of medium chain triglycerides has been shown to induce ketosis in humans [66]. Due to their short fatty adipor1 chain lengths, medium chain trigycerides do not underlie the regulation imposed on long chain fatty acids and they undergo
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LDS BBs were found to
2018-11-12
LDS BBs were found to respond to ET-1 stimulation with a decrease in cell shortening. Furthermore, our findings that BQ123, but not BQ3020, blocked the negative shortening response to ET-1 are consistent with those of Izumi and co-workers (Izumi et al., 2000) and indicate an ETA receptor-mediated ef
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br Results br Discussion Supplementation
2018-11-12
Results Discussion Supplementation of the p38 MAPK inhibitor SB203580 has been identified to enhance cardiomyogenesis of human embryonic stem PXD101 at a relative narrow range of 1–10μM whereas higher concentrations >15μM inhibited or blocked cardiac differentiation (Graichen et al., 2008). T
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Previous reports have suggested that WNTs modulate BMP signa
2018-11-12
Previous reports have suggested that WNTs modulate BMP signaling by promoting C-terminal phosphorylation of SMAD1/5, key components of the BMP signal transduction pathway (Fuentealba et al., 2007). Therefore, we compared the phosphorylation of SMAD1/5 in EBs formed in the combination of WNT3A/BMP4 t
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To the best of our knowledge only
2018-11-12
To the best of our knowledge, only three metabolites, L-threonine, butyrate, and vitamin C, have been identified so far that act as epigenetic modulators of ESC self-renewal and/or somatic cell reprogramming (Mali et al., 2010; Shyh-Chang et al., 2013; Wang et al., 2009). Interestingly, L-threonine,
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In conclusion the present study utilized an in vivo
2018-11-12
In conclusion, the present study utilized an in vivo piglet model of hypoxic-preconditioning-induced ischemic tolerance to demonstrate that PC induces proliferation and neurogenesis of endogenous NSPs up to 7days after the hypoxic–ischemic insult. PC appears as a broad, non-invasive and reproducible
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ldv cost Several transcripts that exhibited an expression ch
2018-11-12
Several transcripts that exhibited an expression change triggered by T3 are promising candidates for being responsible for the observed increased cell extension growth of ENS cells in vitro. The calcium dependent cell adhesion molecule cadherin 12 (Cdh12, N-cadherin, 5.6 fold upregulated), the gene
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br Introduction Human embryonic and induced
2018-11-12
Introduction Human embryonic and induced pluripotent stem cells (h/iPSCs) are of considerable interest in developmental biology and regenerative medicine, representing an enormous opportunity for generating patient-specific cells for screening drugs and cell therapies for various diseases. Stem c
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